Blisters are medically referred to as blisters. Small blisters on hands and feet may be caused by ringworm, sweat herpes, eczema and other diseases, which can be combined with the cause of the disease to take daily care, local medication, systemic medication to control the development of the disease. 1. Ringworm: it is caused by fungal infection, treatment should be based on antifungal as the main principle, it is recommended to use bifonazole cream, clotrimazole ointment, miconazole ointment and so on. If the effect of external medicine is not good or the lesion area is large, can be combined with oral itraconazole and other antifungal drugs. 2. Sweat herpes: related to skin allergies, local infections, poor sweating, mental factors, etc., the treatment of topical drugs, such as applying glucocorticoid ointment (halometasone ointment), urea ointment, vitamin E ointment, etc., if the itching is obvious, can be combined with oral antihistamines, such as cetirizine and other drugs. 3. Eczema: In the acute or subacute stage of eczema, there will be blisters, redness and other symptoms. It is recommended to use topical zinc oxide paste, dexamethasone ointment, when the blisters rupture oozing liquid can be used boric acid solution wet compresses, to be oozing to reduce the use of dexamethasone cream and other hormonal ointment. Severe cases can be treated by oral calcium gluconate, vitamin C, loratadine and other anti-allergy treatment to reduce the itching symptoms. Small blisters on hands and feet, if caused by the above factors, need to be targeted treatment, about the specific medication program, should be in accordance with the requirements of the doctor.