Frequent heartburn, no appetite may be related to the presence of chronic gastritis, gastric ulcer and other causes, it is recommended to pay attention to timely. 1. Chronic gastritis: chronic gastritis is a more common type of gastrointestinal disease in the clinic, will make the body in the inflammatory factor under the stimulation of chronic inflammatory lesions of the gastric mucosa, so that the loss of appetite, heartburn, stomach pain. 2. Gastric ulcer: frequent heartburn, no appetite may also be due to the presence of gastric ulcers, such a situation will make the gastric mucosa in the high gastric acid, pepsin environment is infringed upon, resulting in localized inflammatory injury, often manifested as epigastric pain, heartburn, no appetite. Frequent heartburn, no appetite may also have other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, give targeted treatment or treatment.