Patients with severe abdominal bloating after chemotherapy for nasopharyngeal cancer can be treated with drugs promoting gastrointestinal dynamics under doctor’s guidance, and they can also combine with diet and exercise to regulate. Nasopharyngeal cancer chemotherapeutic drugs are highly toxic, which will produce toxic side effects on normal tissues and cells and cause gastrointestinal reactions, such as stomach bloating, abdominal distension and vomiting. You can choose drugs to promote gastrointestinal movement, such as domperidone and metoclopramide, which can enhance gastrointestinal peristalsis. In terms of diet, you should eat more easily digestible food, such as fish porridge, lean meat porridge and egg porridge, which can increase nutrition and reduce the burden on the gastrointestinal tract. In addition, one should try to get out of bed and walk properly and massage the abdomen can help promote intestinal peristalsis and improve gastric dilatation and abdominal distension. It is suggested that patients with severe abdominal distension after chemotherapy for nasopharyngeal carcinoma should go to the hospital in time and take effective treatment under the doctor’s guidance.