Treatment with metformin helps patients get pregnant when they have diabetes or have polycystic ovary syndrome with islet resistance. If the patient does not have these diseases taking metformin will not benefit the patient and will not achieve the desired effect. Patients with diabetes mellitus are endocrine disorders that can affect a woman’s fertility, as well as predispose her to ketoacidosis or other special conditions after pregnancy. Patients can help women to get pregnant after using metformin to regulate their constitution before pregnancy. Patients with polycystic ovary syndrome and islet resistance are usually obese and have sex hormone 6 disorders. The use of metformin can help patients to restore normal blood sugar level and weight control, which helps to regulate the hormone level of patients, and also helps to restore the normal ovulation of patients, so it helps patients to conceive.