Sudden discontinuation of Haloperidol Melitrexin Tablets may cause some adverse reactions, but usually does not rebound. Flupirtirtide Melitrexin Tablets are mainly used for mild to moderate depression and anxiety, and neurasthenia. The drug is a combination of haloperidol and melitrexine, haloperidol is one of its traditional antipsychotic drugs with some sedative effects. When the use of the drug is suddenly stopped, it produces some withdrawal symptoms such as nausea, vomiting pain, anxiety, agitation, insomnia, headache etc. It makes people mistakenly think that it is a rebound of symptoms, but these symptoms are actually common adverse reactions after sudden discontinuation of the drug, not a rebound of the disease. The drug is not suitable for long-term use and is prone to cause dependence, which can be treated by changing the drug. However, the change of medication should be carried out under the guidance of the doctor, to avoid the sudden discontinuation of the drug caused by adverse reactions. It is recommended that patients take medication in accordance with medical advice.