A two-year-old baby with a fever of 40 degrees Celsius usually has a high fever, so parents are advised to give the child timely antipyretic treatment, which can be oral antipyretic medicine ibuprofen or acetaminophen, one of the two drugs can be chosen. After taking antipyretic drugs, drink more warm water to promote sweating, which is conducive to cooling. However, care should be taken not to sweat too much to avoid causing hypothermia or dehydration. Do not use two antipyretic drugs in combination or alternately, and the interval between the use of two antipyretic drugs should be at least 4-6 hours. In addition, parents should note that if there is recurrent fever or persistent high fever and the child’s mental state is not good, he or she must go to the hospital in time for routine blood tests, C-reactive protein, chest X-ray and other related tests, and then carry out targeted treatment according to the detected causes.