Plasmacytitis is an inflammation that occurs in the plasma membrane layer. Symptoms and manifestations are different according to the site of infection and the source of infection, such as pleural effusion, pericardial effusion, and joint cavity effusion. 1. Pleural effusion: clinical manifestations include dyspnea, cough, chest pain, chest tightness, shortness of breath, loss of breath sounds, etc., restriction of respiratory movement of the affected side of the chest and fullness of the thorax, such as tuberculosis and other infectious pleurisy is often accompanied by fever. 2. Pericardial effusion: it refers to the accumulation of fluid in the pericardial cavity due to infections such as tuberculosis, septicity and non-infections such as rheumatism and uremia, with clinical manifestations such as panic, tightness in the chest, sedentary respiration, leaning forward, shallow respiration, pallor, drop in blood pressure, decrease in pulse pressure, arrhythmia and other symptoms. In case of tuberculous pericardial effusion, symptoms of tuberculosis toxicity such as fever, night sweating and emaciation may appear. 3. Joint effusion: there will be pain, swelling and discomfort in the joints, and the patient may have restricted activities and mobility. Such as septic arthritis, joint tuberculosis and other pain is more intense. When plasmacytitis occurs, patients should first understand the cause and location of the disease, and treat the symptoms according to the cause of the disease, do not self-medication or fluid extraction to prevent secondary infection. When plasma membrane inflammation occurs, it is recommended to actively treat to prevent further development of the disease. Pay attention to rest, do not exercise, light diet, follow the doctor’s instructions for medication, observe the effect of treatment to avoid adverse reactions.