Rivaroxaban can be used to treat cerebral infarction entrapment. Cerebral infarction entrapment usually refers to the occurrence of cerebral infarction in patients with cerebrovascular entrapment. The 2015 Chinese Guidelines for the Diagnosis and Treatment of Carotid Artery Sandwich suggest that the use of anticoagulation can prevent stroke or death in patients with symptomatic cerebral artery sandwich. In the presence of unstable thrombus, severe stenosis or occlusion, multiple ischemic foci in the same arterial supply area, detection of microembolism, intraluminal thrombus, or pseudoaneurysm, it is recommended to choose anticoagulation therapy, and to maintain anticoagulation therapy for 3-6 months if patients with cerebral vascular entrapment develop ischemic stroke. Rivaroxaban is a new type of oral anticoagulant that can selectively inhibit the active site of coagulation factor Xa, and can be used in the treatment of cerebral artery entrapment. Cerebral artery entrapment should be standardized under the guidance of a doctor, the patient’s condition is different, and the determination of therapeutic drugs or programs should be based on the patient’s condition and comprehensive consideration.