The generic name of Shihuida is levamlodipine benzenesulfonate tablets, which can be taken together with irbesartan hydrochlorothiazide. 1. Clinically, levamlodipine benzenesulfonate is a calcium channel blocker, which can reduce the entry of extracellular calcium ions into vascular smooth muscle cells and reduce the contractile response of resistance vessels; it is mainly used in the treatment of hypertension and angina pectoris. Usually the drug and thiazide diuretics, angiotensin-converting enzyme inhibitors are safe; after taking the drug may appear headache, abdominal pain, nausea and other discomforts, allergic to dihydropyridine antagonists are prohibited, need to monitor the liver and kidney function and blood pressure, pregnant women and lactating women need to be guided by a doctor to use the drug. 2. Irbesartan hydrochlorothiazide belongs to the compound preparation of Irbesartan and hydrochlorothiazide, which can reduce the extracellular volume, lower the peripheral vascular resistance, inhibit vasoconstriction and aldosterone release; it is mainly used in the treatment of essential hypertension. Usually, the drug may cause dizziness, nausea, vomiting and other discomforts; it is forbidden for people with severe liver and kidney function impairment, and pregnant women and lactating women need to use the drug under the guidance of a doctor; when used in conjunction with other antihypertensive drugs, it can enhance the effect of lowering blood pressure and prolong the time of lowering blood pressure. In conclusion, if the antihypertensive effect is poor after taking one antihypertensive drug alone, the above two drugs can be used in combination, which can improve the antihypertensive effect and prolong the duration of antihypertensive; the specific combination program should be decided by the doctor after comprehensive assessment of the condition.