Trimethoprim maleate has various side effects such as gastrointestinal discomfort, dizziness, and headache. The medication should be used under the direction of a physician. Trimethoprim maleate is an oral gastrointestinal motility regulator medication indicated to improve symptoms such as loss of appetite, nausea and vomiting, abdominal pain and diarrhea caused by gastrointestinal dysfunction. A variety of side effects may occur after taking the drug, such as abdominal ringing, diarrhea, constipation, dizziness, headache, rash, thirst, and numbness inside the mouth. However, the occurrence of these side effects varies from person to person. It should be noted that the drug is contraindicated in allergic persons, and used with caution in pregnant women, lactating women, children. People with digestive discomfort should use the drug under the guidance of a physician, and if side effects occur after taking the drug, you need to stop taking the drug and consult a doctor.