The need to take glucose-lowering medication during insulin administration may be due to the fact that blood glucose has not reached the control target with insulin therapy alone, and a combination of medications can provide better control of blood glucose. The specific type of treatment a diabetic should take needs to follow the doctor’s advice. If a diabetic patient’s blood sugar still does not reach the control target on the basis of combined lifestyle and oral hypoglycemic medication, he or she can start oral hypoglycemic medication in combination with insulin on the advice of the doctor. Combined insulin and oral medication regimens can reduce the amount of insulin to varying degrees. For example, insulin in combination with metformin to avoid excessive weight gain can reduce the risk of hypoglycemia while ensuring glucose-lowering effects. When using insulin or glucose-lowering drugs, you need to be under the guidance of your doctor to avoid adverse effects on your body.