Neuroses can cause pain in any area and have no fixed location. Neurosis is also known as neurosis, which is essentially a mental disorder, including neurasthenia, obsessive-compulsive disorder, anxiety disorder, somatization disorder and so on. The occurrence of this disease is generally related to psychosocial factors, the patient’s personality traits form the basis of the onset of the disease, the clinical symptoms are more complex and varied, and can involve multiple systems. To diagnose neurosis, all organic diseases must be excluded, and the diagnosis of neurosis can only be considered after careful examination and exclusion of all diseases. The most common cause of pain is the head, patients often feel tension headache, heavy pressure, tightness, like a hoop, or the feeling of wearing a hat. Secondly, it is easy to involve the gastrointestinal tract, easy to have stomach pain, stomach bloating, diarrhea or constipation, patients also often have palpitations, chest tightness, general weakness. After diagnosis, treatment should be directed at their mental disorders, commonly used anti-anxiety and antidepressant drugs, such as haloperidol melittin and duloxetine.