Omeprazole can generally be taken twice a day, but the specific dosage is related to the patient’s condition and drug dosage form. Omeprazole is a proton pump inhibitor, can play a role in inhibiting the secretion of gastric acid, clinically often as chronic gastritis, gastric ulcer, reflux esophagitis, duodenal ulcer and other diseases of the treatment, the drug most of the cases need to be taken 1 to 2 times a day, the eradication of Helicobacter pylori infection, the routine use of omeprazole is 2 times a day. However, it depends on the patient’s condition. For example, patients with peptic ulcer usually need to take omeprazole enteric-coated tablets 1 or 2 times a day, and reflux esophagitis usually needs to be taken 1 or 2 times a day. Omeprazole must be taken by the doctor’s guidance, patients should not take the drug at will, and then if there are serious adverse reactions, such as headache, diarrhea, nausea, vomiting, etc., the drug should be stopped in time and seek medical attention.