Vascular blockage cannot be self-healed and needs to be treated with regular medication or surgical methods. Vascular blockage can occur on the basis of atherosclerosis, where there is rupture of plaque and localized formation of acute thrombus, leading to vascular occlusion. Some patients fall into the category of atheroembolism, where dislodgment of emboli within the circulation leads to vascular occlusion. Vascular occlusion leads to tissue necrosis, is not completely curable, and requires aggressive treatment. Blocked blood vessels need to be given antiplatelet, lipid-lowering and plaque-stabilizing medications, such as aspirin and atorvastatin, and some patients need anticoagulation, commonly known as rivaroxaban. Patients with acute vascular blockage can also undergo surgical treatment, through which the thrombus can be removed, and some patients can have a stent implanted to improve the symptoms caused by vascular blockage. Patients with blocked blood vessels should go to the hospital and be treated under the guidance of a physician.