The drug named amlodipine benzenesulfonate tablets, for calcium antagonist type antihypertensive drugs, long-term use may cause cardiovascular system diseases, neurological disorders, digestive system diseases and other adverse reactions. 1. Cardiovascular diseases: edema is the main adverse reaction of amlodipine benzenesulfonate tablets, which is relatively common and mainly occurs in the lower limbs, and may also cause other cardiovascular diseases, such as cardiac arrhythmia, tachycardia, chest pain, hypotension, fainting and so on. 2. Neurological disorders: common symptoms include headache, hyperalgesia, peripheral neuropathy, sensory abnormalities, tremor, vertigo and so on. 3. Digestive system diseases: mainly loss of appetite, constipation, dyspepsia, dysphagia, diarrhea and so on. Amlodipine benzenesulfonate tablets contraindications for dihydropyridine drugs or allergy to drug components, long-term use of adverse reactions are mostly related to body tolerance, some patients may disappear after a long period of time after the application, if intolerable recommended timely hospitalization, and according to the doctor’s instructions for active treatment.