Sudden peeling of the hands, may be due to the hands in contact with chemical stimuli, can also be considered the emergence of ringworm, sweat herpes, exfoliative dermatitis and other skin diseases. 1. Chemical irritation: in daily life, the hand skin may be in contact with washing powder, detergent and other chemical products, so that the hand protective oils and fats are reduced, if at the same time not timely rubbing and coating moisturizing products, can appear in the palm of the hand, fingers and other parts of the dry, peeling skin. 2. Ringworm: when the dermatophytes invade the palm of the hand, between the fingers, the local skin can be rough, thickened, dry and flaky, and easy to crack and bleed in winter. 3. Sweat herpes: special type of hand eczema, first appear deep in the small blisters, can be fused into large blisters, dry after the formation of collar-like flaking, and with itching. 4. Exfoliative dermatitis: at the beginning, the skin becomes red in pieces, 1~2 days can quickly spread to the whole body, the skin of the affected area is dry, bright red, the skin surface quickly occurs can be successively shed scales, occurs in the palm and plantar parts, there are gloves, sock-like shedding. The hands in the appearance of blisters, flaking and other dermatological manifestations, need to consult a doctor in a timely manner to identify the cause of the disease, the cause of the symptomatic treatment.