IgA Nephropathy is possible to develop to UTI, but whether it will develop to UTI mainly depends on the severity of the disease, the type of pathology and the treatment effect. If the condition is mild and the treatment effect is good, it may not develop into uremia; if the condition is serious and the treatment effect is poor, it may develop into uremia as the disease progresses. The main pathological features of IgA nephropathy are proliferation of glomerular mesangial cells and increased stroma. The pathologic changes are varied, and the degree of pathology varies in severity, and can involve almost all pathological types of glomerulonephritis, such as mesangial proliferative glomerulonephritis, mild lesion type, focal proliferative glomerulonephritis, intracapillary proliferative glomerulonephritis, crescentic glomerulonephritis, and so on. If the patient’s condition is mild, such as focal proliferative glomerulonephritis, slight lesion type, etc., the treatment effect is good and the condition is under control, and it may not develop into uremia; if the condition is more serious and a large amount of proteinuria is seen, such as intracapillary proliferative glomerulonephritis, etc., the treatment effect is not good, and with the progress of the disease, it may develop into uremia. Patients who find IgA nephropathy are recommended to visit regular hospitals in time and standardize the treatment under the guidance of doctors.