Progesterone is taken away from meal times, mainly to reduce gastrointestinal reactions, relieve discomfort and facilitate the absorption of the drug. Progesterone is a progestin, which can cause dizziness, headache, dazzling, nausea, vomiting and other adverse reactions to occur. Progesterone capsules are irritating to the stomach and may cause vomiting when taken at meal times, and the drug is not better absorbed. Therefore, it is usually recommended to take it in the evening or 1 hour after breakfast, while taking progesterone capsules for 2 hours before eating other foods in order to facilitate better absorption of the active ingredients in the drug and avoid stimulation of the stomach. In addition, progesterone capsules are used more often in clinical practice, and most patients may experience dizziness after taking them for 1 hour, so it is recommended to take them before bedtime to reduce the occurrence of dizziness. During the period of oral progesterone, the patient’s diet should be light, and pay attention to rest. Progesterone is a prescription drug and should only be taken under the guidance of a medical professional and with the appropriate indications.