Simeglutide is used by preparing a new needle and injection pen, expelling the air, selecting the appropriate dose, injecting the drug and completing the injection. Simethicone is indicated for blood glucose control in adults with type 2 diabetes mellitus, and the steps of use are as follows. 1. Check the needle and injection pen. The name of the injection pen must be clarified to prevent getting the wrong drug, followed by confirming whether the solution is transparent and colorless, and then take a new needle to place the needle on the injection pen and connect it firmly. 2. Discharge air. The way to expel air is to turn the dose selection button, aligned with the airflow check mark, aligned and then press the delivery button, at this time, you will find that a drop of solution appears on the tip of the needle, suggesting that the air has been correctly discharged. 3. After the expulsion of air is complete, the appropriate dose should be selected. Adjustment is made by the dose selection knob, selecting a dose of 0.25 mg, 0.5 mg, or 1 mg according to the physician’s instructions. 4. Insert the needle into the skin, at this time, you should ensure that you can see the display on the display window, after pressing the continuous administration button, after the administration of the drug, the display window will slowly return to zero, the metered dose display window to return to 0, at this time, the needle should continue to be retained under the skin and wait for about 6 seconds to make sure that it has been fully injected, and then remove the needle. When bleeding occurs, gentle pressure should be applied. Use with caution: contraindicated in pregnancy; contraindicated in individuals with hypersensitivity to the active ingredient or to any of the excipients in the product; contraindicated in individuals with a personal history or family history of medullary thyroid carcinoma (MTC) or in patients with multiple endocrine neoplasia syndrome type 2. If an allergic reaction occurs, discontinue the drug immediately and seek medical attention. It is recommended to be under the supervision of a physician or nurse practitioner if performing simethicone for the first time.