There is no clinical children cough at night how to do the most effective statement, may be allergic cough, cough variant asthma and other conditions, the patient needs to follow the doctor’s instructions to take medication, general measures and so on. 1. Allergic cough: children cough at night may be allergic to some substances indoor caused by the need to avoid contact with allergens, to maintain indoor hygiene, etc., if necessary, also need to comply with the doctor’s orders to use loratadine, cetirizine and other antihistamines treatment. 2. Cough variant asthma: this disease is mostly related to genetic and environmental factors, and can also be manifested as night cough. It can be treated with glucocorticosteroids such as fluticasone inhalation and β2 agonists such as salbutamol as prescribed by the doctor. The treatment can be accompanied by leukotriene modifiers such as montelukast. Parents are advised to seek prompt medical attention to identify the cause of their child’s nighttime cough, and to take proactive and targeted treatment.