Coughing at night causes sleeplessness, need to clarify whether it is respiratory allergic diseases or infectious diseases. If it is allergic diseases such as bronchial asthma, you can use albuterol inhalation aerosol antispasmodic and asthma, but also oral montelukast sodium, ibastine anti-inflammatory, anti-allergic, cough treatment, can be effective in relieving the cough at night. In case of infectious diseases including bronchitis, pneumonia or even tuberculosis infection, antibiotic treatment including penicillin, cephalosporin I, cephalosporin II and ofloxacin can be considered. The anti-infective reduces the leakage from the bronchial tubes above the lungs and controls the severity of the infection to relieve coughing symptoms, while budesonide aerosol can also be added to achieve anti-inflammatory, asthma and cough relief, which is ideal for respiratory allergies caused by coughing at night and not being able to sleep.