EBV is also known as human herpesvirus type 4. When leukemia is infected with human herpes virus after transplantation, fever, rash, swollen lymph nodes and other manifestations will appear. 1. Fever: Human herpes virus secretes special toxin after infection, which enters the hypothalamus after passing through the blood circulation, thus causing abnormal function of the body temperature center and the phenomenon of fever. Moreover, since leukemia patients have just undergone transplantation, their body’s ability to resist diseases is weaker and they are prone to persistent fever. 2. Skin rash: the body resistance is weaker after leukemia transplantation, so skin rash will appear after the invasion of human herpes virus. 3. swollen lymph nodes: this is mainly due to the fact that after the virus invasion, the inflammation will stimulate the lymph nodes, resulting in reactive enlargement of the lymph nodes. Usually, when the disease subsides, the lymph nodes will gradually return to normal, so there is no need to worry too much. After leukemia transplantation, patients will remain immunocompromised for a long time, so they are susceptible to human herpesvirus infection. Therefore, it is recommended to take good protection against the virus, and actively treat any infection.