Eczema and hives are essentially allergic reactions, but there are some differences in the length of the disease and the manifestations of the lesions. Eczema is generally caused by internal factors such as various medical diseases (such as chronic cholecystitis, tonsillitis, intestinal parasitosis, etc.), endocrine and metabolic changes (such as menstrual disorders, pregnancy, etc.), neuropsychiatric factors, genetic factors and other factors based on the stimulation of external factors and the onset of the disease is slow, the course of the disease is protracted, and often develops into chronic eczema. The skin lesions are usually found on the face, ears, hands, feet and other parts of the skin that are easily exposed, and in severe cases can spread throughout the body, often symmetrically distributed. The lesions are polymorphic, often appearing as pinhead to corn-sized papules and papules on an erythematous basis, and in severe cases, small blisters may appear, often fusing into patches, with unclear boundaries, and the papules gradually spreading around the lesions. The skin is often broken and oozing due to intolerance of itching and scratching, and hot water washing can aggravate the lesions. In contrast, urticaria is an allergic disease of the skin and mucous membranes. It starts rapidly with itchy skin, followed by red papules of varying diameters, round, oval or irregular in shape, which can be isolated or expanded and fused into patches, with an uneven skin surface and an orange peel-like appearance. Within a short time the local edema of the skin subsides, the maculopapular rash and gradually disappears with no trace at all, the duration of the lesions usually does not exceed 24 hours, but new rashes can occur one after another, constantly. Eczema and urticaria are both inextricably linked to allergies in summary, but the differences between the two are also obvious and treatment should be treated differently.