Rosuvastatin is commonly known as Rosuvastatin Calcium, Acipimox and Rosuvastatin Calcium can be taken together. The mechanism of action of acyclovir and Rosuvastatin calcium is different. Studies have shown that the two can be used together to treat elderly patients with mixed hyperlipidemia, with remarkable efficacy, which can comprehensively regulate the patient’s blood lipid levels and reduce the probability of cardiovascular disease, so acyclovir and Rosuvastatin calcium can be taken at the same time. Acipimox is a nicotinic acid derivative, mainly used for lowering triglycerides, which can inhibit the separation of adipose tissue, reduce the release of free fatty acids from adipose tissue, and reduce the concentration of thyroglobulin and total cholesterol in the blood by inhibiting the synthesis of very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL). Rosuvastatin calcium is the third generation of statin drugs, has obvious lipid-lowering effect, especially on LDL cholesterol has a strong transfer and removal power, but also inhibit platelet aggregation, reduce inflammation of the body, is the first choice of lipid-lowering drugs. It is necessary to pay attention to those who are allergic to the active ingredients and any excipients of Acipimox, those with peptic ulcers, those with severe renal injury, pregnant women as well as breastfeeding women are prohibited to use Acipimox. And patients may experience adverse reactions such as reddening of the skin and itching after taking it. It is forbidden to use Rosuvastatin Calcium in patients who are allergic to Rosuvastatin Calcium, patients with myopathy, patients with severe renal impairment, patients with active liver disease, pregnant and lactating women. And patients may experience headache, dizziness, constipation and other adverse reactions after use. It is recommended that patients should use these two drugs under the guidance of a doctor, do not use without authorization to avoid delay.