If the skin becomes allergic, red and swollen after applying the cream, first of all, you need to immediately stop the use of such creams and also give targeted anti-allergy treatment. If only mild allergic reactions occur, there is no need for deliberate treatment, because mild allergic reactions can generally be improved to a great extent in 1-2 weeks after stopping the use of creams. For more serious allergic reactions, you can take oral anti-allergy medication for targeted treatment, such as loratadine tablets. Of course, you can also choose topical drugs to improve the itching, redness and swelling of the skin and other clinical symptoms, such as glyburide lotion, which is more commonly used in clinical practice and can effectively improve allergic reactions. Allergic skin reactions after the application of creams are a common clinical complication. For patients with allergies or a history of allergies, it is important to choose topical creams carefully to effectively avoid allergies.