Red tongue tip, yellow thick and greasy tongue coating, and cracks in the center may be caused by liver and gallbladder fire, internal heat in yin deficiency, and deficiency of both qi and yin (deficiency of both qi and yin fluids). It is recommended that medications such as Gentian and Liver Pills, Angelica Longhui Pills, Di Zhen Granules, Er Zhi Pills, Liu Wei Di Huang Pills, and Xin Jia Huang Long Tang be used for treatment under the guidance of a physician. Patients with high liver and gallbladder fire often show dizziness, red face, red eyes, bitter mouth, irritability, constipation, yellow urine, etc. They can be treated with medicines that purify the liver and gallbladder, calm the liver and extinguish the wind, such as Longdian Diarrhea Pill and Angelica Longhui Pill. Patients with yin deficiency and internal heat may have symptoms such as night sweating (abnormal sweating after going to sleep, but sweating stops after waking up), redness of the cheekbones, dry mouth, etc. They can be treated with medicines that nourish the liver and kidney, nourish yin and clear heat (nourish yin and clear away the heat evils), and the commonly-used medicines include Di Zhen Granules, Er Zhi Pills, and Hexa Wei Di Huang Pills. Patients with deficiency of qi and yin may show symptoms such as dry throat, dry mouth, night sweating, fatigue, shortness of breath, etc. They can be treated with prescriptions such as Xinjia Huanglong Tang Plus Reductions and Sha Shen Maidong Tang Plus Reductions. All of the above conditions may cause the symptoms of red tongue tip, yellow thick and greasy tongue coating, and cracks in the middle. If medication is needed, it is recommended to use it under the guidance of doctor’s diagnosis.