A white particle in the eye may be caused by a variety of diseases such as conjunctival stones, lid gland cysts, and wheals, and the following are common: 1. Conjunctival stones: also known as ophthalmic stones, are caused by the aggregation of various substances shed from the conjunctiva, resulting in ocular stones, which may not be treated if there are no symptoms, but should be surgically removed if symptoms such as pain, fear of light, and foreign body sensation occur. If there are other primary conditions, such as conjunctivitis and blepharitis, you will need antibiotic drops to treat the primary condition. 2. Blepharoplasty cysts: also known as chalazia, are caused by the blockage of the glandular opening of the face plate gland, which blocks the discharge of the glandular secretions from the blepharoplasty gland, causing them to accumulate in the gland and stimulate the tissue around the gland, which may lead to bacterial infection and white pus particles in the eye. This can be treated with local heat and a combination of antibiotic eye ointment to promote the dissipation and absorption of incipient and small lid cysts. 3. Wheals: Bacterial infection of the sebaceous glands or lid glands at the root of the eyelash follicles at the edge of the eyelid, resulting in the formation of white granules; some patients with wheals do not require medication and can disappear on their own within 1-2 weeks. If symptoms persist and do not improve, antibiotic treatment and surgical drainage of the pus are required. In addition, this condition can be caused by other eye pathologies, such as conjunctival lid spots, early pterygium, conjunctival foreign bodies, and sarcoidosis. Therefore, patients who find white particles in their eyes along with pain, foreign body sensation, and pus flow in the eye should seek prompt medical attention to identify the cause for targeted treatment.