A granular sensation of foreign body rubbing the eye may be caused by the real presence of foreign body in the eye, or it may be that there is no actual foreign body in the eye, but the feeling of granular sensation of foreign body rubbing the eye occurs because of a certain disease. It is recommended to consult a doctor promptly and treat accordingly according to different situations: 1. Foreign body in the eye: If a foreign body such as tiny particles in the air or bugs enters the eye, the patient will have the feeling of particle sensation rubbing the eye, which is usually not accompanied by eye pain, redness, swelling, photophobia and other symptoms. Some of the smaller foreign bodies can be gradually discharged on their own with tears and contraction of the orbicularis oculi muscle. However, if some of the foreign bodies are adhesive, or if the foreign bodies are large and deep, you need to go to the ophthalmologist immediately to have them removed. 2. Ingrown eyelashes: Some people have ingrown eyelashes due to genetics or inflammation, and the eyelashes face the eyeball to produce the feeling of rubbing against the particles, accompanied by photophobia and tearing. The treatment method for impingement usually needs to be chosen according to the cause and the patient’s own situation, and can usually be treated by surgery, massage therapy, freezing or laser therapy, or extraction of the impingement. 3. Conjunctival stones: Due to conjunctival stones, patients experience increased secretions, which gradually form non-calcified stones in the conjunctiva, producing a feeling of granular foreign body rubbing against the eye, sometimes visible as yellowish-white granules. It can be treated with antibacterial eye drops such as levofloxacin drops under the guidance of a doctor, or pick out the stones with a disposable needle after local anesthesia and use antibacterial eye drops for a few days after picking out; 4. Conjunctivitis: Patients with conjunctivitis often blink their eyes, have a feeling of granular foreign body rubbing, and also have red eyes, dryness, and photophobia. Usually requires the topical use of broad-spectrum antibiotics and glucocorticoid eye drops, and most patients can be cured after active treatment; 5. Keratitis: In addition to the feeling of granular foreign body friction, patients also experience a sharp decrease in vision, photophobia, and tearing. It usually requires cause-specific treatment under the guidance of a doctor, such as antiviral drugs like fluconazole eye drops and antibacterial drugs like oxyfloxacin eye drops. When medication is not effective and keratitis is more severe, surgical treatment such as conjunctival masking and therapeutic corneal transplantation can be performed. In addition to the more common diseases mentioned above, eye diseases such as eyelid lesions, mydriasis, and dry eye may also cause patients to have the sensation of a foreign body rubbing against the eyeball. Once a patient has this condition, if it can be recovered in a short period of time, treatment is usually not necessary. If the condition fails to resolve over a long period of time and affects daily life, patients should visit an ophthalmologist as soon as possible to identify the cause and provide targeted treatment.