What happens when amiodarone is dispensed in saline

First of all, the standard preparation method of amiodarone is to use 5% dextrose as solute, and it is not possible to use saline to configure. Because amiodarone is a substance formed by substituting two iodines on the benzene ring, for now, as the iodine substituent is very unstable, and it is easy to fall off, degradation and deterioration, when using saline to configure, it will make the amiodarone degradation and can’t play the role of the drug’s efficacy, and the saline contains chlorine ions, chlorine ions can easily take the place of the position of the iodine on the amiodarone, and then the formation of the precipitate which is not easy to be watered. precipitates. When intravenous injection will produce serious consequences, clinical use of amiodarone injection should be prepared with 5% dextrose, in the clinic should master the preparation of various drugs, especially like amiodarone this kind of special drugs, can only be configured with dextrose injection.