Since the country has liberalized the two-child policy, many older women have responded to the call to have a second baby, so what preparation is needed for that? In the medical sense, older women are those who are older than 35 years old. As they grow older, especially after 35 to 40 years old, the reserve function of women’s ovaries slowly starts to decline; even women’s endocrine function gradually declines and menstrual irregularities occur; even if they get pregnant, there is a possibility that the embryo stops developing because of insufficient luteal support or problems with the embryo itself. So it is not so easy to want a good baby at this time. So first of all, what initial preparations should be made? It is recommended to consult a gynecologist and check the six gonadal tests on the 2nd-4th days of menstruation to understand the ovarian reserve function; monitor the basal body temperature by yourself to understand whether there is ovulation or not (you can download a relevant APP online); check estradiol and progesterone 5-7 days before menstruation to understand the luteal function. 2.Check cervical cancer screening TCT+HPV before pregnancy (don’t worry too much if the result is normal within five years). 3.Gynecological ultrasound 2-7 days after menstruation to exclude endometrial lesions. If the first child was delivered by cesarean section, the healing of the cesarean section scar should also be understood. 4.The husband’s semen routine examination is needed for eugenics for relatively senior fathers.