In medicine, there is no such thing as cheap and effective medication for chronic obstructive pulmonary disease, and the specific medication used is related to the patient’s condition. Chronic Obstructive Pulmonary Disease (COPD) is clinically categorized into stable and acute exacerbation periods. Stabilization period is mainly to prevent the main, acute exacerbation period, in the clear bacterial infection, need to actively anti-infection treatment. The fundamental purpose of stabilizing rehabilitation is to prevent acute exacerbation, improve mobility, and restore damaged cardiopulmonary function as much as possible, thus effectively preventing and slowing down the decline of cardiopulmonary function. Active smoking cessation is required, and appropriate inhaled medications such as salbutamol, ipratropium bromide, formoterol, salmeterol, etc., are selected if necessary. In case of acute exacerbation, antibiotics, such as amoxicillin, cefuroxime, levofloxacin and other medications are needed when bacterial infection is clearly identified, and systemic short-term intravenous hormone therapy, such as methylprednisolone, can also be used under the guidance of the doctor, which can quickly control the symptoms of shortness of breath and chest tightness. Bronchodilators such as salbutamol and ipratropium bromide can also be used in combination with the patient’s symptoms to improve symptoms. If a patient with chronic obstructive pulmonary disease is not feeling well, it is recommended that the patient go to the hospital and be treated under the guidance of a doctor. The above drugs need to be used under the guidance of a physician.