Small white pus particles on the face, consider the following cases: 1. Impetigo: is caused by Staphylococcus aureus, Streptococcus haemolyticus infection, clinical treatment can choose azithromycin dry mix suspension, cefixime capsule orally, local wet application of povidone-iodine solution, furacilin solution, followed by external application of fusidic acid ointment, mupirocin ointment for treatment. 2. Acne: is caused by endocrine disorders Acne propionibacterium infection is caused, treatment can be oral minocycline hydrochloride capsules with diphenhydramine capsules, local application ofloxacin gel, clindamycin phosphate gel for treatment.