The hazards of genetic diseases include: 1, affecting physical and intellectual development: such as Down’s syndrome, the emergence of mental retardation, intellectual development backwardness, autism, etc.; 2, functional damage: such as congenital heart disease, hemophilia, etc., affecting hematopoietic function, coagulation function, heart function development, etc.; 3, hereditary offspring: with hereditary, the harm to the family is relatively large. For the prevention of genetic diseases, it is necessary to do premarital and prenatal checkups, to monitor the growth and development of the fetus in time after pregnancy, and to terminate the pregnancy if necessary for the fetus found to have serious genetic diseases.