In the pain clinic work, often encountered a strange phenomenon. Many patients with acute and chronic pain, when we propose to give him a pain point block, always reflexively ask a question, this is a “closed needle”, will not be harmful to the body? Pain point block is also commonly known as “closed needle”. In fact, in the world, “closed needle” is the most widely used, the most cost-effective chronic pain treatment method. The so-called “closed needle”, in fact, is the drug composition contains local anesthetic and a small amount of hormones. Among them, the local anesthetic to play a rapid analgesic, relieve the role of muscle spasm; and play a major role is the hormone component. Chronic pain patients, the pain site of the tissues, muscles and joints are often accompanied by aseptic inflammation, a variety of cytokines, pain-causing substances, such as the release of the pain response, spasm, and local blood circulation disorders; and pain, local circulatory disorders will aggravate the release of cytokines, pain-causing substances, and so on, which in turn aggravate the inflammation, and each other to form a vicious circle. The drug composition of “closed needle” contains a small amount of hormone components, which can significantly inhibit the inflammatory reaction of local tissues, significantly improve the blood circulation of local tissues, thus instantly relieving pain. Closed needle in the hormone component to block the “inflammation → cytokines, pain-causing substances release → pain, local circulation disorders → inflammation” this vicious circle, not only indicators, more can cure! In the clinic, many tenosynovitis, frozen shoulder, muscle strain, heel pain, lumbar myofascial syndrome patients, some of them once the closed needle can be “fixed”, some patients need about two times, and then with some auxiliary treatment, can be basically cured. Of course, although the “closed needle” is the most cost-effective, but the application should never be abused. Because it contains a small amount of hormones, so the closed needle can not be applied for a long time, generally about 5-6 times a year can be used, there will not be any side effects. If the closed needle is used three times in a row and the effect is not good, it should not be used again. If the patient has serious hypertension, diabetes and other diseases, the use should also be careful. In the 1980s, the “closed needle” was widely popular in China and was abused by many charlatan doctors, resulting in some serious complications. As a result, many people in our country are skeptical about closed needles. Worldwide, “closed needles” are still one of the most commonly used treatments for chronic pain. Chinese people should no longer be suspicious of “closed needles”.