What is the probability of BCG-induced lymphatic tuberculosis?

The probability of BCG causing lymphatic tuberculosis is about 3.55/100,000, which is a low probability of occurrence. BCG is a live bacterial vaccine made from a suspension of attenuated Mycobacterium tuberculosis, which is injected to stimulate the body to produce a cellular humoral response for the prevention of tuberculosis. Common adverse reactions include fever, malaise, localized redness, swelling, pus, and ulceration about 2 weeks after vaccination, and in a few people, infections such as localized abscesses, lymphadenitis, osteomyelitis, and, in severe cases, BCG disseminated infection. According to the 2018 National Adverse Reaction Monitoring System for Preventive Vaccination, the incidence of lymphadenitis caused by BCG vaccination is 3.55/100,000, and lymph node enlargement of more than 1cm or abscess after BCG vaccination suggests the presence of lymphadenitis, which needs to be treated in the hospital. BCG vaccine belongs to China’s planned immunization vaccine, belongs to the category of mandatory vaccination, it is recommended that parents pay close attention to the reaction after vaccination, if necessary, timely medical treatment.