There is a lump in the patient’s cheek that moves and hurts a little, and the common causes are mainly the following: a. Acute infections such as mouth ulcers, sinusitis and pharyngitis can cause swollen submandibular lymph nodes, which manifest as local lump-like changes with swollen lymph nodes. At this time, patients can control the acute inflammation in the body through active anti-infection treatment, prompting the swollen lymph nodes to gradually subside, thus achieving better treatment results. Secondly, if patients have malignant tumor of nasopharynx, malignant tumor of thyroid gland or malignant tumor of oral cavity, which causes cancerous metastasis of lymph nodes in the cheek, it can also be manifested as local lumps and accompanied by pain. In this case, drug treatment alone cannot make the lymph nodes recede as soon as possible. It is necessary to improve CT and ultrasound examinations to clarify the location of the primary tumor and then perform resection of the primary tumor and lymph node dissection as soon as possible. After surgery, chemotherapy and radiotherapy can be combined to kill the tumor cells in the body and remove the enlarged lymph nodes as much as possible.