Tofacitib is not always safe, there is a possibility of adverse reactions to this product, and it needs to be used appropriately under the supervision of a doctor. Tofacitib is a drug for the treatment of rheumatoid arthritis, can also be used in combination with methotrexate or other non-biological improvement of the condition of the anti-rheumatic drugs. There is a possibility of adverse reactions to this product, and patients may develop serious infections, malignant tumors, lymphoproliferative disorders, gastrointestinal perforation, and abnormal laboratory tests (e.g., abnormal platelet values). It should be noted that allergy to any of the components of the product is prohibited, for women of childbearing potential, the use of this product should be family planning and contraception, for the elderly the incidence of infection is higher, for the elderly treatment should be cautious. If you need to use the drug, it is recommended to use the drug under the guidance of a doctor, not blindly self-medication to avoid adverse effects and other safety issues.