The pain in the body after infusion of levofloxacin is generally due to drug reaction, the reaction of the disease itself, the osmotic pressure of the drug is relatively high. 1. drug reaction: levofloxacin will produce a certain stimulation reaction to the stomach, causing creatine and lactic acid and other metabolites accumulation, back pain, patients should stop the drug in time, under the guidance of the doctor to use cefixime or cefpodoxime ester and other anti-inflammatory drugs for treatment, can alleviate the patient’s uncomfortable symptoms, allergic to the drug is prohibited. 2. The reaction of the disease itself: levofloxacin is generally the treatment of inflammatory diseases, inflammatory diseases will appear body aches, fatigue and other symptoms, resulting in patients appearing after the infusion of levofloxacin body aches, patients should pay attention to rest, can do some moderate exercise. 3. Higher osmotic pressure of drugs: Higher osmotic pressure of drugs will increase the burden on the heart, causing patients to experience body pain, limb weakness and other symptoms, appearing after the infusion of levofloxacin body pain, patients should pay attention to rest, under the guidance of the doctor to slow down the infusion rate. It is recommended that patients go to the hospital in time for examination and pay attention to their physical condition as well as body care.