Gastroretentive poisoning, first of all, we have to stop the drug immediately, and at the same time to give vomiting, gastric lavage, diarrhea, so that the residual gastroretentive in the body as soon as possible out of the body, in order to prevent the patient to continue to absorb. At the same time can be given rehydration, diuretic, to promote the metabolism and excretion of gastrointestinal fuan. Secondly, some symptomatic treatment should be carried out, such as dystonia caused by gastroparesis poisoning, scopolamine can be used for intramuscular injection. Cause liver and kidney function damage should be given to protect the liver and kidney. Particular attention should be paid to the fact that if there is myocardial damage, nutritional myocardial treatment should be given.