The main ingredients of meal replacement powder are plant-based foods, moderate replacement of some of the main meals on health effects, long-term replacement of staple foods with meal replacement powder has diarrhea, malnutrition and other side effects. The fiber content in meal replacement powder is relatively high, fiber can promote gastrointestinal peristalsis, resulting in the body to shorten the time to absorb and digest food easily induced diarrhea, meal replacement powder has a certain amount of protein, but mainly plant protein, the content can not meet the body’s metabolic needs, long-term replacement of staple foods with meal replacement powder is likely to cause protein deficiency, resistance to decline, skin flaccidity, elasticity and other changes. At the same time, meal replacement powder in vitamin A, vitamin D, vitamin E and iodine, zinc and other trace elements content is also relatively low, lack of nutrients easily induced calcium deficiency, vision loss, sexual dysfunction and other changes.