The survival rate of patients with advanced liver cancer with bone metastasis cannot be generalized, it should be considered according to the patient’s own condition, overall treatment plan, clinical manifestation, etc. At present, the median survival time of liver cancer transplant recipients with recurrent tumor metastasis is 7~16 months. The median survival time of liver cancer transplant recipients after tumor recurrence and metastasis is 7~16 months. For this kind of patients, they should pay attention to rest in their daily life, strictly prohibit alcohol and liver-damaging drugs, and their family members should give certain psychological support to the patients, so as to reduce the bad emotions and improve the quality of their survival. Patients can reduce the adverse effects of the disease through “early detection, early diagnosis, early treatment”, many patients are likely to survive for a long time, and patients are advised to establish confidence in treatment.