Microwave and its thermal effects: usually called the frequency of 300-300,000MHZ, wavelength 1mm-1m high-frequency electromagnetic waves for microwave, its frequency between high-frequency waves and laser, its heating principle is different from other electromagnetic waves, laser and high-frequency waves whose energy is given by the surface of the tissue, known as the external heating method, while the microwave due to the energy of each photon below 10-3ev, can not produce ionization effect . It has certain optical properties similar to the role of its waveform can be appropriately shaped wireless aggregation, so that the energy is concentrated, to facilitate local heating, it takes the biological body itself as a heat source, most of the human tissue is composed of polar molecules such as water and protein, under the action of the microwave electric field moment, polar molecules along the direction of the microwave electric field for the orderly arrangement of the orientation of the movement, and with the alternating high-frequency electric field and Back and forth rotation, in the process of rotation and adjacent molecules produce similar friction, collision and generate heat, thus generating non-conductive heat, is a kind of internal heating method, and heat does not emit, thermal effect, good balance, thermal stability. Bone tissue is different from the high water content of fat and visceral organs, it contains low water content, it is the microwave heating of objects inside and outside the same time, without the process of heat transfer, heating up quickly, after the cessation of cooling is also fast. In the microwave radiation field, the tissue damage is uniform. The common methods of microwave thermal effect treatment: 1, microwave local heat therapy requires control of the temperature of about 42-45 ℃. 2. Microwave tissue coagulation is a new development in microwave therapy, using microwave antennas to concentrate energy in a small area to coagulate the tissue and produce immune effects, controlling the temperature at 65-100℃. Feasibility of in situ inactivation of bone tumors: 1. Malignant bone tumors can be completely separated in situ, and because they are surrounded by covered muscles, nerves and blood vessels, malignant primary bone tumors can be completely freed through skilled surgical techniques; 2. It is convenient for in vivo thermotherapy, and as long as appropriate measures are taken, the tumor can be completely inactivated in vivo and normal tissues are preserved intact; 3. Bone cells have strong regenerative ability and fast crawling replacement. The basic idea and process of microwave antenna array induced high temperature in situ inactivation technology for malignant bone tumors: The method is to separate the tumor segment bone from the surrounding normal tissue through fine surgical dissection, leaving a thin layer of normal tissue on the surface of the tumor to meet the requirements unique to tumor surgery. The microwave antenna is used to safely introduce microwave energy into the tumor bone, and through the array arrangement of the antenna, the microwave energy is directly and evenly distributed in the tumor body, and the specially designed temperature control system not only ensures the high temperature required for tumor inactivation, but also ensures that the surrounding normal tissues are under temperature control. It is not affected by high temperature. After microwave inactivation, the defective bone tissue is then effectively repaired with homogeneous bone particles compounded with bone cement, and the regenerative vascularization of the inactivated bone is nearly completed in 6-12 months as observed by the instrument. Advantages: 1. Only in situ separation of tumor (including important vascular nerve bundles and uninvaded muscles) is done, which preserves the stability and continuity of bone and joint structure intact and maximizes the function of limbs and joints, and discards the disadvantages of current limb preservation techniques of bone amputation and destruction of joint structure; 2. Microwaves are introduced into the center of tumor by special wires, so that the generated high temperature is conducted from the inside to the surface, which can not only kill the The tumor cells can be killed without destroying the continuity of the bone and minimizing the damage to the normal tissues, while the microwave antenna is inserted to reduce the radiation damage to the patient’s body and medical personnel. At the same time, using the high temperature heat conduction effect of microwave and sufficient action time, the tumor area can be thermally inactivated in an expanded range to ensure that a sufficient surgical safety boundary can be obtained to reduce the possibility of local recurrence after surgery; 4. Effectively repair bone tissue defects after microwave inactivation and provide solid biomechanical support, and eventually obtain effective recanalization; 6. In addition to thermal effects, microwaves also induce anti-tumor effects, which may be due to T-cell or NK cell-mediated immune responses.