Cough reflex receptors are located in the mucosa of the larynx, trachea and bronchi. The receptors above the large bronchi are sensitive to mechanical stimuli, while those below the secondary bronchi are sensitive to chemical stimuli. Afferent impulses are transmitted via the vagus nerve to the medulla oblongata, triggering a series of coordinated reflex responses that cause the cough reflex. Tests related to impaired respiratory reflex regulation: Respiratory movement test: is to check for healthy movement of breathing in a rhythmic motion. Inhalation is immediately followed by exhalation, and after a short interval, the next breath is taken. Generally short inhalation and slightly longer exhalation, can change due to excitement, fear and strenuous exercise, etc. If the respiratory movement changes for a long time, it is pathological. The four common clinical types of abnormal respiratory rhythms are tidal breathing, interstitial breathing, Kussmaul breathing, and sigh-like breathing. Respiratory kinetics: An adjunct to the pulmonary and pleural examinations, respiratory kinetics are examined by palpation to confirm visual clinic findings. The palms of both hands are placed flat on the symmetrical part of the patient’s chest during the examination. The thumbs of both hands meet at the front median line, and when the patient inhales deeply, the thorax expands, and the two hands abduct with the expansion of the thorax, and the distance between the thumbs and the front median line can be observed to determine whether the respiratory mobility of both sides of the thorax is symmetrical. Physical examination: referred to as physical examination, also known as physical examination, physical examination or health examination, is a method for doctors to use their senses, examination instruments, laboratory equipment, etc. to directly or indirectly examine the physical condition of patients, the purpose of which is to collect objective information about the health of patients, early detection, prevention of hidden diseases. The contents include: 1) history of exercise and disease; 2) measurement of morphological indicators; 3) physiological function tests; 4) determination of body composition; 5) special examinations (laboratory tests, x-ray, ECG, EEG, EMG, echocardiography, muscle needle biopsy, etc.). Urine examination: including routine urine analysis, detection of organic components in urine (such as urine red blood cells, white blood cells, etc.), quantitative determination of protein components, urine enzyme determination, etc. Urine examination has a very important value for clinical diagnosis, judging the efficacy and prognosis.