Pain on one side of the throat when swallowing can be associated with a variety of diseases, such as upper respiratory tract infections and acute tonsillitis. Such symptoms caused by inflammation are often treated with medication depending on the cause and the degree of symptoms. Upper respiratory tract infections such as colds can cause the throat to become congested and swollen, dry and painful. This can manifest as pain when swallowing. Drink plenty of water, rest, reduce physical exertion, symptomatic drug treatment; if caused by bacterial infection can be oral amoxicillin, cefuroxime, etc.. Acute tonsillitis can be seen when the tonsils are red and swollen, purulent secretions increase. It can lead to fever, headache and other symptoms. Antibiotics, such as penicillin and azithromycin, are usually taken to control the infection, and glucocorticosteroids, such as systemic dexamethasone and prednisone, are also used to reduce the inflammatory response when localized swelling is obvious. What causes this symptom should be clearly diagnosed after examination by a specialist, and drug treatment should be carried out under the guidance of a doctor, and should not be taken indiscriminately.