Toothache implies that the patient may suffer from oral diseases such as pulpitis, angina, trigeminal neuralgia and other diseases. 1. Oral diseases such as pulpitis: the pulp is infected by bacteria, which leads to the emergence of pulpitis, the patient’s pain is more intense, when encountered with hot and cold stimuli, the stimulus will cause sensitive pain. Other oral diseases such as deep caries, periodontitis, etc. will also have the manifestation of toothache. 2. Angina: If the patient’s teeth do not have any abnormality can consider whether it is caused by angina. Because the nerves that innervate the heart and the nerves that innervate the jawbone have the same spinal nerve center. Therefore, when angina patients have symptoms, there will be radiating pain in the lower jaw, which will be manifested as toothache. 3. Trigeminal neuralgia: When trigeminal neuralgia occurs, severe pain occurs in the area where the trigeminal nerve is located, and many patients will have a toothache as the first symptom. This pain usually lasts for a short period of time, and when the trigeminal neuralgia is relieved, the toothache will also disappear. When a toothache occurs, patients should go to a regular hospital in time to identify the cause of the disease, and under the guidance of the doctor to carry out targeted treatment.