Burning sensation in the chest with acid reflux is usually associated with reflux esophagitis, chronic gastritis, bile reflux gastritis and so on. 1. Reflux esophagitis: burning sensation in the chest with acid reflux may be caused by reflux esophagitis, which is usually related to the destruction of anti-reflux barrier and dysfunction of esophageal acid contouring. 2. Chronic gastritis: burning sensation in the chest accompanied by acid reflux may also be caused by chronic gastritis, chronic gastritis patients usually have indigestion, loss of appetite, nausea and acid reflux. 3. Bile Reflux Gastritis: Bile reflux into the stomach, patients usually have abdominal fullness, heartburn, belching (hiccups), acid reflux, vomiting and other symptoms. Burning sensation in the chest with acid reflux may also have other causes, it is recommended that patients go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor for treatment.