Large lower eye bags may be caused by genetic factors, traumatic factors, or diseases such as nephritis. It can be eliminated through medication, physical therapy and surgery. 1. Genetic factors: If the bags under the eyes are caused by congenital heredity, you can take physical treatments such as laser and radiofrequency to utilize the energy to reach the dermis layer to tighten it and dissolve the excess fat so as to eliminate the bags under the eyes, or you can directly excise the excess part, such as blepharoplasty and other surgical treatments. 2. Traumatic factors: traumatic injury to the orbicularis oculi muscle and orbital septum damage will appear under the eyes bags phenomenon, can be under the guidance of the doctor topical antibiotic drugs, such as erythromycin ointment, mupirocin ointment, etc., can play a role in anti-inflammatory, swelling, so as to alleviate the symptoms of the elimination of the phenomenon. 3. Nephritis: nephritis can also cause the phenomenon of large bags under the eyes, this phenomenon can be prescribed oral diuretics, such as hydrochlorothiazide, chlorothiazide, etc., have diuretic, reduce the role of edema. There are many reasons for the bags under the eyes, it is recommended that patients go to the hospital, clear causes, standardized treatment under the guidance of the doctor.