Patients with sore thighs, can not sleep, must clarify the causes of soreness, and then symptomatic treatment, intravenous infusion, local treatment, oral drug therapy, mainly as follows: 1, intravenous infusion: if the patient’s thigh soreness is caused by sciatic nerve compression, can be carried out to reduce the swelling of the sciatic nerve, anti-inflammatory treatment, can be sedated mannitol and dexamethasone on the nerve root to reduce swelling, can relieve the lower limb radioactive pain. 2, local treatment: If the patient’s thigh pain is caused by the accumulation of lactic acid in the thigh muscles, you can use local heat compresses, moxibustion heat compresses or infrared irradiation of the thigh area, which can promote local blood circulation and relieve the feeling of soreness and pain. 3, oral medication: patients can take oral anti-inflammatory and pain relief drugs, including Celecoxib capsules and meloxicam tablets, which can also better relieve the symptoms.