The causes of swollen eyes and swollen legs are mainly considered in four points: the first point, hypoproteinemia, long-term malnutrition leads to a decrease in the ability of albumin synthesis, which leads to hypoproteinemia, a decrease in the osmotic pressure of intravascular colloids, and tissue edema, which is mainly manifested in swollen eyes and swollen legs, as depressed edema. The second point, liver disease, most often seen in the end stage of various liver diseases, liver failure can not synthesize albumin, the inactivation of aldosterone is also reduced, which leads to sodium retention in the body, tissue edema, which is manifested as swelling of the legs and ophthalmoplegia. The third point, end-stage renal manifestations, mostly seen in nephrotic syndrome, massive water loss, hypoproteinemia, thus causing interstitial edema. The fourth point, cardiac disease, acute left heart failure often presents with lower limb edema and facial swelling.