The urology clinic often encounters patients who come to the clinic with discharge from the urethral orifice, most of whom are filled with nervousness, fear and anxiety, complaining of no history of unclean sex, and suspecting that they have contracted STDs through bedding in public baths or frequent business trips. So, is the discharge from the male urethral orifice a sexually transmitted disease? The male urethral orifice is divided into two kinds of secretions: physiological and pathological secretions: a. Physiological secretions Normal male urethra has more small glands distributed under the mucosa, and there are urethral bulb glands within the muscle bundle of the deep transverse plane of the perineum, and the urethral bulb glands are larger. All the above glands pass through the duct to the urethra. During sexual excitement and penile erection, the secretion of these glands increases and a small amount of colorless, clear secretion can appear at the urethra, which can be pulled into long threads and play a role in lubricating the urethra. Normal adult male, during sleep at night there will be penile erection more than 3 times, the appearance of the urethral orifice secretions sticky on the underwear, dry, a small number of scattered white spots, usually no symptoms of urethral discomfort, belong to the normal physiological situation. Second, pathological discharge 1. sticky purulent discharge. When there is a large amount of yellowish-white viscous purulent discharge from the external urethra, accompanied by painful discomfort in the distal urethra, dirty underwear and a history of unclean sex, it is usually gonococcal urethritis, a type of sexually transmitted disease. 2. Thin, cloudy discharge. When there is a small amount of thin, cloudy discharge from the urethra, which can be found by squeezing the urethra before the first urination in the morning, with itching and discomfort in the urethra, or with frequent and urgent urination, and scattered yellow spots visible in the underwear, it is usually a non-gonorrheal urethritis caused by Chlamydia, Mycoplasma, Candida albicans or Trichomonas infection, which is a relatively common clinical sexually transmitted disease, and usually has a history of unclean sex. 3. Bloody discharge, commonly caused by urethral injury or penile cancer. When penile cancer is combined with local infection, bloody purulent discharge with foul smell may appear. In short, when there is discharge from the external urethra, there is no need to be nervous and specific analysis is needed. If there is a history of unclean sexual life, and at the same time there are symptoms of urethral discomfort, and the discharge is yellow-white sticky-purulent or thin and turbid purulent, there is a high possibility of STD. If there is no history of impure sex, there is a possibility of transmission via infected bedding, but it is very unlikely. The possibility of transmission via soaking is even smaller. Therefore, it is not always an STD when there is urethral discharge from the male urethra.